A blister, which is also called a vesicle by medical professionals, is a raised portion of skin that is filled with fluid. You’re probably familiar with blisters if you’ve ever worn ill-fitting shoes for too long.

This common cause of blistering produces vesicles when friction between your skin and the shoe results in layers of skin separating and filling with fluid.

Blisters are often annoying, painful, or uncomfortable. But in most cases, they aren’t a symptom of anything serious and will heal without any medical intervention. If you ever have unexplained blistering on your skin, you should see your healthcare provider for a diagnosis.

Cold sores are red, fluid-filled blisters that form near the mouth or on other areas of the face. In rare cases, cold sores may appear on the fingers, nose, or inside the mouth. They’re usually clumped together in patches. Cold sores may persist for two weeks or longer.

A common virus called herpes simplex causes cold sores. They can spread from person to person through close contact, such as kissing. The sores are contagious even when they’re not visible.

There’s no cure for cold sores, and they may return without warning. Certain medications can be used to treat cold sores and prevent them from coming back.

Cold sores are caused by the herpes simplex virus. There are two types of the herpes simplex virus. The herpes simplex type 1 virus (HSV-1) usually causes cold sores, and the herpes simplex type 2 virus (HSV-2) usually causes genital herpes.

The actual sores are similar in appearance for both forms of the virus. It’s also possible for HSV-1 to cause sores on the genitals and for HSV-2 to cause sores on the mouth.

Visible cold sores are contagious, but they may be spread even when they can’t be seen. You can get the herpes simplex virus by coming in contact with people with the herpes simplex virus. This may happen through kissing, sharing cosmetics, or sharing food. Oral sex may spread both cold sores and genital herpes.

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Journal of Clinical & Experimental Dermatology Research
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